ISSN 1941-5923


Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more

Published: 2015-02-26

Inadvertent Transmission of Polycystic Kidney Disease in Kidney Transplantation

Amit Langote, Andrea Mazarova, John Mahoney, Brian Blew, Greg A. Knoll

(Division of Nephrology, Department of Medicine, Ottawa Hospital, Ottawa, ON, Canada)

Am J Case Rep 2015; 16:115-118

DOI: 10.12659/AJCR.892456

Background: Although organ donors are rigorously tested, occasionally an unidentified donor disease can be transmitted to the recipient. These conditions include malignancies, infections, and, rarely, congenital diseases.
Case Report: We report a case of an inadvertent transmission of polycystic kidney disease from a 40-year-old trauma victim to both kidney recipients. There was no family history of renal disease in the donor. The renal allografts gradually increased in size with the development of cysts and functioned for 10 and 14 years.
Conclusions: We report a case of inadvertent transmission of polycystic kidney disease from an unsuspecting deceased donor to both the recipients through renal allograft. Both the grafts lasted long enough to suggest that polycystic kidneys from deceased donors can be considered for transplantation.

Keywords: Kidney Transplantation, Polycystic Kidney Diseases, Tissue Donors, Unrelated Donors

Published: 2015-02-24

Atypical Hemolytic-Uremic Syndrome: A Case Report and Literature Review

Arsalan Rafiq, Hassan Tariq, Naeem Abbas, Roopalekha Shenoy

Am J Case Rep 2015; 16:109-114

DOI: 10.12659/AJCR.892907

Published: 2015-02-22

Bony Fusion in a Chronic Cervical Bilateral Facet Dislocation

Alexa Bodman, Lawrence Chin

Am J Case Rep 2015; 16:104-108

DOI: 10.12659/AJCR.892173