ISSN 1941-5923

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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2014-09-20

Horizontal Liver Cleft: A Rare Anatomic Variant

Yong Han Ting, Kian Soon Lim

(Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore, Singapore)

Am J Case Rep 2014; 15:401-403

DOI: 10.12659/AJCR.892274


Background: Improvements in hepatobiliary surgical techniques, with increased usage of segmental and subsegmental resection, make accurate preoperative radiological assessment delineation of the liver segments ever more crucial. Conventionally, this is done by drawing imaginary straight planes along the portal and hepatic veins. We herein report a rare case of a horizontal cleft between the superior and inferior liver segments seen on CT.
Case Report: A 74-year-old female patient with a known medical history of ovarian cancer with peritoneal metastasis and retroperitoneal lymphadenopathy was referred to our department for CT to assess disease response after treatment. On contrast-enhanced CT, apart from the ovarian cancer, the liver had a smooth, well-defined horizontally orientated cleft that broadly divided the organ into 2 halves. The cleft contained the right and left main portal veins, and consequently had a curved down-sloping configuration accommodating the curved course of these veins. This liver cleft was present from an earlier CT study performed 3 years ago, and there was no history of preceding liver surgery.
Conclusions: To the best of our knowledge, this is the first report of the anomaly of a horizontal liver cleft, which may be attributed to early cessation of the embryological formation of the liver. This liver cleft also illustrates the difficulties in liver segmentation using Couinaud’s classification.

Keywords: Congenital Abnormalities, Liver, Radiology




Published: 2014-09-17

In-Stent Restenosis Exacerbated by Drug-Induced Severe Eosinophilia after Second-Generation Drug-Eluting ...


Hiroki Yagi, Eisuke Amiya, Jiro Ando, Masafumi Watanabe, Koichi Yanaba, Masako Ikemura, Masashi Fukayama, Issei Komuro

Am J Case Rep 2014; 15:397-400

DOI: 10.12659/AJCR.891106

Published: 2014-09-14

Severe Hypercalcemia Complicating Recovery of Acute Kidney Injury due to Rhabdomyolysis


Lisa Aimee Hechanova, Seyed Ali Sadjadi

Am J Case Rep 2014; 15:393-396

DOI: 10.12659/AJCR.891046