ISSN 1941-5923

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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2014-11-23

Spontaneous Hemarthrosis Following Fibrinolytic Therapy for Acute Myocardial Infarction: A Case Report and Literature Review

Mahmoud M. Ramadan, Iqbal S. Khan, Ousama Mahdi

(Department of Cardiology, Mansoura University, Faculty of Medicine, Mansoura, Egypt)

Am J Case Rep 2014; 15:514-517

DOI: 10.12659/AJCR.892138


Background: Despite the widespread use of fibrinolytic therapy and the numerous reports on its bleeding complications, spontaneous hemarthrosis following fibrinolytic therapy is quite rare.
Case Report: We describe in this report a patient with no previous history of articular disease who developed a spontaneous right knee bloody effusion following fibrinolytic therapy using rt-PA for acute ST-elevation myocardial infarction. Furthermore, we provide a review of all cases of spontaneous hemarthrosis documented so far in the literature.
Conclusions: Several pre-existing joint diseases may predispose to hemarthrosis following fibrinolytic therapy, even in patients who deny previous or current articular disorders. Therefore, hemorrhage should be considered in the differential diagnosis of mono-arthritis following fibrinolytic therapy for STEMI.

Keywords: Hemarthrosis, Myocardial Infarction, Thrombolytic Therapy




Published: 2014-11-21

Resolution of an Acute Aortic Syndrome with Aortic Valve Insufficiency Post-PCI


Pedro G.M. de Barros e Silva, Thiago Aquino, Marcos V. Resende, Ivo Richter, Cecilia M. Barros, Vanessa G. Andrioli, Antonio C. Baruzzi, Caio C.J. Medeiros, Valter Furlan

Am J Case Rep 2014; 15:508-513

DOI: 10.12659/AJCR.891301

Published: 2014-11-19

Massive Purulent Pericardial Effusion Presenting as Atrial Fibrillation with Rapid Rate: Case Report and ...


Amit Kathrotia, Mohan R. Hindupur

Am J Case Rep 2014; 15:504-507

DOI: 10.12659/AJCR.889851