24 October 2008
Pulmonary pseudallescheriasis
Seiji Okimasa, Satoshi Shibata, Shinkichiro YoshiokaAm J Case Rep 2008; 9:411-414 :: ID: 869422
Abstract
Background: Pseudallescheria boydii (P. boydii) is the most frequent etiological agent of eumycotic mycetoma and is an occasional agent of otomycosis, keratitis, endophthalmitis, meningitis, brain abscess, and osteomyelitis. However, this condition is very rare, and is usually observed in immunocompromised patients. Here, we report a case of pulmonary pseudallescheriasis in a patient without immunity disorder.
Case Report: The patient was a 25-year-old construction worker. He presented to our hospital with hemoptysis, and a chest X-ray revealed nodular shadows in the left upper lung field. Chest computed tomography (CT) revealed infiltration with cavitary nodules. The results of fl exible bronchoscopy examination suggested pulmonary aspergillosis. Pyrexia was observed at the same time. The patient was treated with micafungin sodium (MCFG), but showed no improvement. Later, fungi suspected to be P. boydii were detected on Sabouraud’s agar. Antifungal therapy was changed to administration of voriconazole (VRCZ). Despite the disappearance of pyrexia, the abnormal shadow did not disappear completely, and left upper lobectomy was performed. The patient’s postoperative course was uneventful, and he has been followed up on an outpatient basis without any recurrence.
Conclusions: It is important to consider this disease in cases in which medication using amphotericin B and/or MCFG is not effective under a diagnosis of pulmonary aspergillosis. It is recommended to perform a culture test and PCR without delay. In addition, we believe that surgery for locally invasive disease as in this case may be of value in preventing rapid and fatal dissemination.
Keywords: fungal infection, Lung, Pseudoallescheria
In Press
14 Mar 2024 : Case report
Potential Indicators of Intestinal Necrosis in Portal Venous Gas: A Case Report of an 82-Year-Old Woman on ...Am J Case Rep In Press; DOI: 10.12659/AJCR.942966
05 Mar 2024 : Case report
Simultaneous Transcatheter Closure of a Ventricular Septal Defect and Pulmonary Valvuloplasty: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.942032
06 Mar 2024 : Case report
Successful Healing of Periapical Pathology with Partial Pulpotomy in a Mature Permanent Molar: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.942937
12 Mar 2024 : Case report
Successful Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus with Celecoxib: A Promising Therapeu...Am J Case Rep In Press; DOI: 10.12659/AJCR.943244
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250