25 May 2009
Clearing off wisconsin solution used in liver transplantation in pediatric patients
Ahmet Mahli, Demet Coskun, Gizem Ilvan, Sema Oncul, Hakan Sozen, Aydin DalgicAm J Case Rep 2009; 10:72-74 :: ID: 869656
Abstract
Background: Organ preservation is an important component of transplantation process. It ensures the vitability of the donor’s organ until the time of its implantation in the receiver.
Case Report: A 7.5-month-old, 7300 gram female infant who had been diagnosed with neonatal cholestatic hepatitis at the age of one month and who had never undergone surgery before was operated on for liver transplantation. The left lobe of the liver donated by the mother was applied 500 ml of Wisconsin solution for preservation. At the end of anhepatic phase, K+ value of the receiver was 4.5 meq/L. Before the neohepatic phase, a cleansing solution of 100 ml of 20% human albumin in 1000 ml of 5% dextrose was prepared to clean the donor’s liver off University of Wisconsin (UW) solution and K+ in particular. Until the fluid drained from the donor’s liver was clear, the donor’s liver was administered 300 ml of the solution. As the washing was considered to be inadequate, this process was sustained by using 800 ml of the washing solution. The first K+ value measured after reperfusion was 5.5 meq/L. The operation was completed without any complications and no problems were encountered during the postoperative 6-month follow-up.
Conclusions: No information was found in literature regarding how much washing solution should be used to reduce the K+ burden that occurs in the receiver as a result of K+ rich UW solution which is used in order to protect the organ during liver transplantation. Organ washing procedure is conventionally extended until the washing solution becomes clear. However, in pediatric cases, we propose that the washing procedure has to be extended not until the washing solution becomes clear but until 100 ml of human albumin 20% in 1000 ml of 5% dextrose solution is used up.
Keywords: University of Wisconson (UW) solution, pediatry, liver transplantation (LTX)
In Press
16 Mar 2024 : Case report
Castleman Disease Presenting in the Neck: A Report of 3 Cases and a Literature ReviewAm J Case Rep In Press; DOI: 10.12659/AJCR.943214
16 Mar 2024 : Case report
Early Diagnosis and Successful Empirical Treatment of L1-L2 Spondylodiscitis in a 21-Month-Old Girl: A Case...Am J Case Rep In Press; DOI: 10.12659/AJCR.943010
16 Mar 2024 : Case report
A Rare Autochthonous Case of Hepatic Hydatid Cyst in the Non-Endemic Region of TaiwanAm J Case Rep In Press; DOI: 10.12659/AJCR.943687
17 Mar 2024 : Case report
Contrast-Enhanced Ultrasonography in Diagnosing Intravascular Large B-Cell Lymphoma Infiltrating Liver Sinu...Am J Case Rep In Press; DOI: 10.12659/AJCR.943070
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250