01 September 2003
Bone marrow supression and acute renal failure related to single dose of 500 miligram dipyrone
Kürsad Erinc, Murat Aslan, Filiz Aslan, Cengiz Beyan, Ertan Demirtas FaccCase Rep Clin Pract Rev 2003; 4(2):94-96 :: ID: 429041
Abstract
Background: Nonsteroid anti-inflammatory drugs may cause idiosyncrasy in some susceptible individuals. This case is presented in order to make an impact on a rare form of dipyrone-associated idiosyncrasy.Case Report: A 68-year-old female was hospitalized with dyspnea, pretibial edema and fatigue. Initial complete blood count, hepatic and renal functions were normal. On 4th day of her hospitalization, she was given 500 mg dipyrone because she suffered toothache. In the following days, moderate decrement of the blood cells (WBC: 2.0i103/KL, RBC: 3.00i106/KL, Hb: 9.2 g/dl, Htc: 28%, Platelets: 82i103/KL) and further abnormality of renal function (BUN: 124 mg/dl, creatinine: 7.0 mg/dl) were encountered. On 9th day, renal functions were normal (BUN: 35 mg/dl, creatinine: 0.9 mg/dl). At that time, complete blood count values were as follows: Hb: 9.8 g/dl, Htc: 30.3%, WBC: 5.1i103/KL, Platelets: 237i103/KL. Conclusions: Dipyrone-associated idiosyncrasy may result serious abnormalities in renal and hemopoetic functions. Therefore, using dipyrone must require attention in certain situations.
Keywords: bone marrow suppression, Dipyrone, Idiosyncrasy
44
In Press
05 Mar 2024 : Case report
Simultaneous Transcatheter Closure of a Ventricular Septal Defect and Pulmonary Valvuloplasty: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.942032
06 Mar 2024 : Case report
Successful Healing of Periapical Pathology with Partial Pulpotomy in a Mature Permanent Molar: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.942937
12 Mar 2024 : Case report
Successful Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus with Celecoxib: A Promising Therapeu...Am J Case Rep In Press; DOI: 10.12659/AJCR.943244
13 Mar 2024 : Case report
Recurrent Marginal Zone Lymphoma with Bone Marrow Involvement Detected by ¹⁸F-FDG PET/CT and Biopsy: A Diag...Am J Case Rep In Press; DOI: 10.12659/AJCR.943275
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250