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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2014-07-24

Thyroid Storm Complicated by Bicytopenia and Disseminated Intravascular Coagulation

Yoshinori Tokushima, Yuta Sakanishi, Kou Nagae, Midori Tokushima, Masaki Tago, Motosuke Tomonaga, Tsuneaki Yoshioka, Masaki Hyakutake, Takashi Sugioka, Shu-ichi Yamashita

(Department of General Medicine, Saga University Hospital, Saga city, Japan)

Am J Case Rep 2014; 15:312-316

DOI: 10.12659/AJCR.890519


Background: The clinical presentation of thyroid storm includes fever, tachycardia, hypertension, and neurological abnormalities. It is a serious condition with a high mortality rate. Furthermore, some other complications affect the clinical course of thyroid storm. Although it is reported that prognosis is poor when thyroid storm is complicated by disseminated intravascular coagulation syndrome (DIC) and leukopenia, reports of such cases are rare.
Case Report: A 23-year-old man presented with delirium, high pyrexia, diarrhea, and weight loss of 18 kg over 2 months. According to the criteria of Burch and Wartofsky, he was diagnosed with thyroid storm on the basis of his symptom-complex and laboratory data that confirmed the presence of hyperthyroidism. Investigations also found leukopenia, thrombocytopenia, and disseminated intravascular coagulation,...

Keywords: Disseminated Intravascular Coagulation - complications, hyperthyroidism, Thyroid Crisis



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