ISSN 1941-5923

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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2015-04-24

Unusual Clinical Presentation of Thoracic Tuberculosis: The Need for a Better Knowledge of Illness

Sandra Manca, Alessandro Giuseppe Fois, Luigi Santoru, Rocco Trisolini, Maria Francesca Polo, Salvatore Ostera, Marco Patelli, Pietro Pirina

(Department of Respiratory Disease, University of Sassari, Sassari, Italy)

Am J Case Rep 2015; 16:240-244

DOI: 10.12659/AJCR.892546


Background: Pulmonary tuberculosis (TB), a highly contagious infectious disease, is a significant public health problem all over the world and remains an important cause of preventable death in the adult population. Endobronchial TB is an unusual form of thoracic TB that may be complicated by tracheobronchial stenosis, and bronchoesophageal fistula formation is a very rare complication. Tubercular lymphadenitis can also lead to fistula formation through a process of caseum necrosis and opening of a fistula between the bronchus and oesophagus.
Case Report: We report an uncommon case of thoracic TB in an immunocompetent 73-year-old Caucasian man who presented several problems: bronchoesophageal fistula, endobronchial TB, and mediastinal lymphadenopathy in the absence of contemporary parenchymal consolidation. Furthermore, he presented a normal chest radiograph and mostly unclear and non-specific symptoms at onset.
Conclusions: We emphasize the need for a better knowledge of this illness and awareness that it may have an unusual presentation. In these cases, diagnosis and proper treatment can be delayed, with severe complications for the patient. Pulmonary TB remains a real diagnostic challenge: a normal chest radiograph and nonspecific symptoms do not allow us to exclude this persistent infectious disease.

Keywords: Bronchial Fistula, Tuberculosis, Lymph Node, Tuberculosis, Pulmonary




Published: 2015-04-23

Purulent Pericarditis with Quadruple Valve Endocarditis


Huliyurdurga S. Setty Natrajsetty, Ishwarappa B. Vijayalakshmi, Chitra Narasimhan, Cholenahalli N. Manjunath

Am J Case Rep 2015; 16:236-239

DOI: 10.12659/AJCR.893072

Published: 2015-04-20

Encephalopathy and Hypotonia due to Baclofen Toxicity in a Patient with End-Stage Renal Disease


Mohsin Ijaz, Hassan Tariq, Muhammad Kashif, Jose Gomez Marquez

Am J Case Rep 2015; 16:232-235

DOI: 10.12659/AJCR.893222