ISSN 1941-5923

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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2015-09-04

Varicella Zoster Aseptic Meningitis: Report of an Atypical Case and Literature Review

Walid Ibrahim, Abdel-Naser Elzouki, Ahmed Husain, Lubna Osman

(Department of Internal Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar)

Am J Case Rep 2015; 16:594-597

ID: 894045


BACKGROUND: Neurologic complications can occur with varicella zoster virus (VZV) infection, usually after vesicular exanthem. A review of the literature revealed 3 cases of viral meningitis associated with 6th nerve palsy but without significantly increased intracranial pressure.
CASE REPORT: We report a case of a previously healthy 15-year-old girl with aseptic meningitis as a result of reactivated-VZV infection with symptoms of increased intracranial pressure and reversible 6th cranial nerve palsy but without exanthema.
Diagnosis was made by detection of VZV-DNA in cerebrospinal fluid using polymerase chain reaction and documented high intracranial pressure. Full recovery was achieved after a course of acyclovir and acetazolamide.
CONCLUSIONS: This case demonstrates that VZV may be considered in cases of aseptic meningitis in immunocompetent individuals, even without exanthema, and it may increase the intracranial pressure, leading to symptoms, and causing reversible neurological deficit.

Keywords: Abducens Nerve Diseases, Herpesvirus 3, Human, Intracranial Hypertension, Meningitis, Aseptic



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