ISSN 1941-5923

Logo



Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2015-01-28

A Complication of Tracheobronchopathia Osteochondroplastica Presenting as Acute Hypercapnic Respiratory Failure

Mauricio Danckers, Roy A. Raad, Ronaldo Zamuco, Aron Pollack, Scott Rickert, Caralee Caplan-Shaw

(Division of Pulmonary, Critical Care and Sleep Medicine, New York University Langone Medical Center, New York, NY, USA)

Am J Case Rep 2015; 16:45-49

DOI: 10.12659/AJCR.892427


Background: Tracheobronchopathia osteochondroplastica is a rare benign and often indolent disease. We report the first case of tracheobronchopathia osteochondroplastica (TBO) presenting as acute hypercarbic respiratory failure due to superimposed subglottic submucosal abscess.
Case Report: A 27-year-old man presented to the emergency department in respiratory distress that required mechanical ventilation for acute hypercarbic respiratory failure. Upon extubation the next day, stridor was elicited with ambulation. Spirometry revealed fixed upper airway obstruction. Neck imaging showed a 2.8×2.0×4.0 cm partially calcified subglottic mass with cystic and solid component obstructing 75% of the airway. Surgical exploration revealed purulent drainage upon elevation of the thyroid isthmus and an anterolateral cricoid wall defect in communication with a subglottic submucosal cavity. Microbiology was negative for bacteria or fungi. Pathology showed chondro-osseous metaplasia compatible with tracheobronchopathia osteochondroplastica (TBO). The patient received a course of antibiotics and prophylactic tracheostomy. Since tracheostomy removal 3 days later, the patient remains asymptomatic.
Conclusions: Tracheobronchopathia osteochondroplastica is a rare disease with usually benign clinical course and incidental diagnosis. It may present as acute hypercarbic respiratory failure when subglottic infection is superimposed.

Keywords: Abscess, Airway Obstruction, Asthma




Published: 2015-01-27

Congenital Incomplete Fusion of Superior Mesenteric Artery Mimicking Dissection


Vasu Keshav Sharma, Martin Weng Chin H'ng

Am J Case Rep 2015; 16:41-44

DOI: 10.12659/AJCR.892527

Published: 2015-01-25

Appendectomy and Resection of the Terminal Ileum with Secondary Severe Necrotic Changes in Acute Perforat...


Yuri N. Shiryajev, Nikolay N. Volkov, Alexey A. Kashintsev, Marina V. Chalenko, Yuri V. Radionov

Am J Case Rep 2015; 16:37-40

DOI: 10.12659/AJCR.892471