ISSN 1941-5923

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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2015-03-30

Coconut Atrium in Long-Standing Rheumatic Valvular Heart Disease

Takahisa Onishi, Yuka Idei, Kazunori Otsui, Sachiyo Iwata, Atsushi Suzuki, Toru Ozawa, Koji Domoto, Asumi Takei, Shinya Inamoto, Nobutaka Inoue

(Department of Cardiovascular Medicine, Kobe Rosai Hospital, Kobe, Hyogo, Japan)

Am J Case Rep 2015; 16:191-195

DOI: 10.12659/AJCR.892449


Background: Complete calcification of the left atrium (LA) is called “coconut atrium”, which decreases the compliance of LA, leading to the elevation of LA pressure that is transmitted to the right-side of the heart. The pathogenesis of LA calcification in patients with rheumatic heart disease is unknown; however, possible mechanisms include chronic strain force in the atrial wall and inflammation. We report here a patient with long-standing rheumatic valvular heart disease with coconut atrium.
Case Report: A 76-year-old man presented with breathlessness and leg edema due to right-sided heart failure. He was diagnosed with rheumatic fever at 8 years of age. Mitral commissurotomy and the mitral and aortic valve replacement were previously performed to treat mitral and aortic valvular stenosis. The profile view of the chest X-ray indicated a diffuse calcified outline of the LA wall. A transthoracic echocardiogram revealed pulmonary hypertension and dilatation of both atria. Moreover, computed tomography showed nearly circumferential calcification of the LA wall. Despite intense medical treatment, he succumbed to heart failure. An autopsy demonstrated that the LA was markedly dilated, its wall was calcified, and its appearance was similar to the surface of an atherosclerotic aorta. Microscopic examination revealed intensive calcification in the endocardium. Minimal accumulation of inflammatory cells was noted. Although slight fibrosis was observed, the cardiac musculature was preserved.
Conclusions: To the best of our knowledge, this is the first report that identifies the histological changes of LA calcification associated with long-standing rh... read more

Keywords: Heart Atria, Heart Failure, Rheumatic Heart Disease




Published: 2015-03-27

Endovascular Therapy for Fibromuscular Dysplasia of the Bilateral External Iliac Arteries Visualized with...


Takeshi Niizeki, Mitsunori Ishino, Tatsuro Kitahara, So Yamauchi, Eiichiro Ikeno, Isao Kubota

Am J Case Rep 2015; 16:187-190

DOI: 10.12659/AJCR.893167

Published: 2015-03-25

Multi-Organ Failure Secondary to a Clostridium Perfringens Gaseous Liver Abscess following a Self-Limited...


Sherif Ali Eltawansy, Chandni Merchant, Paavani Atluri, Sukrut Dwivedi

Am J Case Rep 2015; 16:182-186

DOI: 10.12659/AJCR.893046