ISSN 1941-5923

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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2014-10-29

Gallbladder Papillomatosis and Cholecystocolonic Fistula: A Rare Combination

Jenn-Yuan Kuo, Yeun Tarl Fresner Ng Jao

(Department of Gastroenterology, Tainan Municipal Hospital, Tainan, Taiwan)

Am J Case Rep 2014; 15:466-470

DOI: 10.12659/AJCR.891190


Background: Biliary papillomatosis (BP) with sole involvement of the gall bladder or gall bladder papillomatosis (GBP) is very rare. Biliary-enteric fistula, particularly the cholecystocolonic fistula (CCF) type, is also very rare. The combination of both types of lesions in a single patient has never previously been reported in the English literature.
Case Report: We report herein the case of an 81-year-old woman who was diagnosed with both disease entities, which occurred in a cause-and-effect relationship. She underwent resection of the gall bladder with closure of the fistula, and was discharged improved afterwards.
Conclusions: GBP is a premalignant condition that warrants extensive resection. An absent Murphy’s sign or jaundice on physical examination should not rule out this disease or accompanying biliary tract infection because a biliary-enteric fistula may be present. Thorough review of the radiologic images should be performed, since subtle details could be easily missed or dismissed, thus affecting the postoperative course. A CCF should alert the physician that another disease entity is present.

Keywords: Biliary Fistula, Colonic Diseases, Gallbladder Neoplasms




Published: 2014-10-26

Glomus Tumor of the Trachea Managed by Spiral Tracheoplasty


Hsing-Hsien Wu, Yeun Tarl Fresner Ng Jao, Ming-Ho Wu

Am J Case Rep 2014; 15:459-465

DOI: 10.12659/AJCR.891191

Published: 2014-10-24

Management of Spindle Cell Carcinoma of the Maxillary Sinus: A Case Report and Literature Review


Hisham B. Alem, Mohammed K. AlNoury

Am J Case Rep 2014; 15:454-458

DOI: 10.12659/AJCR.891007