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American Journal of Case Reports have been selected for the ESCI - Emerging Sources Citation Index (Thomson Reuters, Web of Science, ISI), launching in November of 2015 as a new edition of the Web of Science.

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Published: 2016-07-22

Patient with Small Cell Lung Carcinoma and Suspected Right Upper Lobe Abscess Presenting with a Purulent Pericardial Effusion

Khushboo Goel, Huthayfa Ateeli, Neil M. Ampel, Dena L’heureux

(Department of Internal Medicine, University of Arizona, Tucson, AZ, USA)

Am J Case Rep 2016; 17:523-528

DOI: 10.12659/AJCR.898079


BACKGROUND: Cardiac tamponade caused by pericardial effusion has a high mortality rate; thus, it is important to diagnose and treat this condition immediately. Specifically, bacterial pericarditis, although now very rare, is often fatal because of its fulminant process.
CASE REPORT: We present a case of a 61-year-old man with metastatic small cell lung cancer undergoing chemotherapy who presented with fatigue, poor appetite, and altered mental status. He was found to have a large-volume pericardial effusion with tamponade physiology. He underwent emergent pericardiocentesis. The pericardial effusion was nonmalignant, with cultures growing Streptococcus pneumoniae. It was only after his emergent pericardiocentesis that previous imaging from one month prior was able to be reviewed, which showed possible right upper lobe abscess.
CONCLUSIONS: Most pericardial effusions in cancer patients are related to their malignancy, either due to direct metastasis or secondary physiologic effects. This case is a unique example of a lung cancer patient presenting with a pneumococcal pericardial effusion, which in itself is a rare phenomenon. This case report demonstrates the importance of considering early antibiotic therapy in patients presenting with pericardial effusion, especially given the high mortality rates of infectious pericardial effusions.

Keywords: Cardiac Tamponade, Pericardial Effusion, Pneumococcal Infections, Small Cell Lung Carcinoma




Published: 2016-07-21

Intestinal Lymphangiectasia: Insights on Management and Literature Review


Mohamad J. Alshikho, Joud M. Talas, Salem I. Noureldine, Saf Zazou, Aladdin Addas, Haitham Kurabi, Mahmoud Nasser

Am J Case Rep 2016; 17:512-522

DOI: 10.12659/AJCR.899636

Published: 2016-07-20

Septic Pulmonary Embolism Caused by Infected Pacemaker Leads After Replacement of a Cardiac Resynchroniza...


Salah A.M. Said, Rogier Nijhuis, Anita Derks, Herman Droste

Am J Case Rep 2016; 17:507-511

DOI: 10.12659/AJCR.898009