ISSN 1941-5923

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Welcome to the American Journal of Case Reports

Clinical case reports are an invaluable first-hand source of evidence in medicine and a tool most often used in practice to exchange information and generate a more expanded search for evidence. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis,  treatment effectiveness, causes and outcomes of disease. However limited their... read more


Published: 2014-08-20

Successful treatment of recurrent cholangitis by constructing a hepaticojejunostomy with long Roux-en-Y limb in a long-term surviving patient after a Whipple procedure for pancreatic adenocarcinoma

Konstantinos Tsalis, Nikolaos Antoniou, Zambia Koukouritaki, Dimitrios Patridas, Leonidas Sakkas, Dimitrios Kyziridis, Charalampos Lazaridis

(4th Department of Surgery, Aristotle University of Thessaloniki, G.Papanikolaou Ho, Thessaloniki, Greece)

Am J Case Rep 2014; 15:348-351

DOI: 10.12659/AJCR.890436


Background: Cholangitis may result from biliary obstruction (e.g., biliary or anastomotic stenosis, or foreign bodies) or occur in the presence of normal biliary drainage. Although reflux of intestinal contents into the biliary tree after hepaticojejunostomy appears to be a rare complication, it is important to emphasize that there are few available surgical therapeutic techniques.
Case Report: A 74-year-old woman presented to our hospital after 17 years of episodes of cholangitis. The patient had undergone a pancreatoduodenectomy (Whipple procedure) 18 years earlier due to pancreatic adenocarcinoma. The reconstruction was achieved through the sequential placement of pancreatic, biliary, and retrocolic gastric anastomosis into the same jejunal loop. The postoperative course was uneventful and the patient received adjuvant chemotherapy. Approximately 6 months after the initial operation, the patient started having episodes of cholangitis. Over the next 17 years she experienced several febrile episodes presumed to be secondary to cholangitis. A computing tomography (CT) scan of the abdomen revealed intrahepatic bile ducts partially filled with orally administered contrast material (Gastrografin). Magnetic resonance cholangiopancreatography (MRCP) showed dilatation of the left intrahepatic bile ducts. A percutaneous transhepatic cholangiography showed that the bilioenteric anastomosis was normal, without stenosis. Based on these findings, a diagnosis of a short loop between the hepaticojejunostomy and the gastrojejunostomy permitting the reflux of intestinal juice into the biliary tree was made. During the re-operation, a new hepaticojejunal anastomosis... read more

Keywords: Anastomosis, Roux-en-Y - methods, Cholangitis - therapy, Pancreatic Neoplasms - pathology, Pancreatic Neoplasms - surgery




Published: 2014-08-17

Metastatic Hepatocellular Carcinoma to Parotid Glands


Abdel-Naser Elzouki, Hisham Elkhider, Khalid Yacout, Ahmed Al Muzrakchi, Shaikah Al-Thani, Omer Ismail

Am J Case Rep 2014; 15:343-347

DOI: 10.12659/AJCR.890661

Published: 2014-08-14

Fibroepithelial Polyp of the Epiglottis


Zainab Farzal, Seckin O. Ulualp, Dinesh Rakheja

Am J Case Rep 2014; 15:340-342

DOI: 10.12659/AJCR.890924