Figure 5. (A) Hepatic core needle biopsy: Hematoxylin/eosin-stained slides show hepatic parenchyma almost completely substituted by a middle-size cell population characterized by nuclei with membrane irregularity, with incision, dispersed chromatin, and slightly eosinophilic cytoplasm. A mixed infiltrate composed of lymphocytes, plasma cells, histiocytes, and numerous eosinophil granulocytes were also present around the lesions. There was moderate fibrosis, with disappearance of the portal spaces. (B) Immunohistochemistry showed positivity for CD1a.