12 October 2020: Articles
Widely Disseminated Cryptococcosis Manifesting in a Previously Undiagnosed Human Immunodeficiency Virus (HIV)-Positive 18-Year-Old
Unusual clinical course, Challenging differential diagnosis, Unusual setting of medical care
John Howard A , Thomas Z. Thompson A , Rodger D. MacArthur D , Amyn M. Rojiani A , Joseph White A*DOI: 10.12659/AJCR.924410
Am J Case Rep 2020; 21:e924410
Figure 1. (A) Low-power view demonstrating the large number of foci of cryptococci in the spleen. H&E. Original magnification 20×. (B) Cryptococcal foci widely disseminated within the subarachnoid space. H&E. Original magnification 200×. (C) Occasional cryptococcal foci within the adrenal cortex. H&E. Original magnification 100×. (D) Widespread cryptococcal foci within the lungs. H&E. Original magnification 100×. (E) Cryptococcal foci seen in multiple sections of bone marrow. H&E. Original magnification 100×. (F) Rare cryptococcal foci were present in the myocardium. H&E. Original magnification 200×. (G) Cryptococcal foci were also seen in the thyroid gland. H&E. Original magnification 100×. (H) Gomori methenamine silver stain identifying cryptococci foci within the adrenal cortex. H&E. Original magnification 100×. (I) Mucicarmine stain identifying cryptococcal foci within the brain. Original magnification 200×.