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08 September 2021: Articles

Histoplasmosis Related to Immunosuppression in a Patient with Crohn’s Disease: A Diagnostic Challenge

Unusual clinical course, Challenging differential diagnosis, Adverse events of drug therapy

Sandro da Costa Ferreira A* , Fernando Jorge Firmino Nóbrega B , Roberta Chaves de Araújo B , Patrícia Holanda de Almeida B , Márcia Guimarães Villanova B , Rodrigo de Carvalho Santana D , Leandra Naira Zambelli Ramalho D , Ana de Lourdes Candolo Martinelli D , Luiz Ernesto de Almeida Troncon A

DOI: 10.12659/AJCR.925345

Am J Case Rep 2021; 22:e925345

Figure 1. (A, B) Granulomatous inflammation in the liver, with the presence of clustered macrophages (H&E, 20 and 40×, magnification, respectively). (C, D) Absence of acid-fast bacilli in granulomas (Ziehl-Neelsen, 20 and 40×, magnification, respectively). (E–G) Presence of small rounded, birefringent, and clustered structures (Gomori-Methanamine-Silver, 20, 40 and 100×, magnification, respectively).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923