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21 October 2020: Articles

A Case of Vaginal Malignant Melanoma Completely Resected by Radical Surgery

Rare disease

Ryuichi Tokumitsu B , Tomoko Hirakawa B* , Mitsutake Yano B , Evgeniya Kirakosyan E , Shimpei Sato E , Kaei Nasu E , Hisashi Narahara A

DOI: 10.12659/AJCR.927462

Am J Case Rep 2020; 21:e927462

Figure 2. Postoperative examinations: (A) Macroscopically, a tumor of size 45×25 mm with a black surface was detected in the posterior vaginal wall (yellow arrows). (B) Hematoxylin and eosin ×4; and (C) Hematoxylin and eosin ×40. Microscopically, the tumor cells were arranged in sheets and nests and exhibited nuclear pleomorphism, an eosinophilic cytoplasm, brisk mitotic activity, and melanin production. Immunohistochemically, the tumor was positive for (D) SOX10 and (E) the Ki-67 labeling index was 70%.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923