26 January 2021>: Articles
Massive Retinal Gliosis in an Infant Microphthalmic Globe: A Case Report
Challenging differential diagnosis, Congenital defects / diseases
Rakan S. Al-Essa E , Hind Manaa Alkatan A* , Maria A. Arafah B , Yasser H. Al-Faky BDOI: 10.12659/AJCR.929363
Am J Case Rep 2021; 22:e929363
Figure 1. (A) The clinical appearance of incomplete cryptophthalmos, with a deeper small microphthalmic globe on the left side. (B) An axial T2-weighted magnetic resonance image showing a microphthalmos with a cyst occupying the right orbital cavity, and a small microphthalmic globe on the left. (C) A histopathologic image of the massive retinal gliosis with an island of ciliary body-pigmented epithelium (original magnification ×200, hematoxylin and eosin). (D) A higher magnification of the proliferating spindle-shaped glial cells (original magnification ×400, periodic acid Schiff). (E) Retinal gliosis showing a strong expression of the glial tissue marker (original magnification ×400, glial fibrillary acidic protein). (F) Glial cells expressing reactivity to synaptophysin (original magnification ×200, synaptophysin).