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16 June 2021: Articles

Role of Intravenous Acyclovir in Treatment of Herpes Simplex Virus Stromal Keratitis with Ulceration: A Review of 2 Cases

Unusual clinical course, Mistake in diagnosis, Unusual or unexpected effect of treatment

Punyanuch Pisitpayat B , Passara Jongkhajornpong D , Kaevalin Lekhanont D , Manachai Nonpassopon A*

DOI: 10.12659/AJCR.930467

Am J Case Rep 2021; 22:e930467

Figure 2. Slit-lamp photographs showing clinical progression of patient No. 2. (A) On day 1, eccentric, well-defined edge anterior one-third of stromal infiltration with overlying epithelial defect. (B, C) On day 3, progression of anterior stromal infiltration and scalloped-shaped border of epithelial defect demonstrated by fluorescein staining. (D) On day 7, multifocal, large, deep and dense anterior stromal infiltration with corneal melting. (E) On day 12 (after 3 days of intravenous acyclovir), improvement of stromal infiltration, but still of stromal melting at center of the lesion. (F) On day 30 (after 1 week of autologous serum eye drops), improvement of corneal melting and decreasing size of epithelial defect.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923