30 May 2021>: Articles
Systemic IgG4-Related Disease Masquerading as Cholangiocarcinoma: A Case Report Underscoring the Importance of Medical History
Challenging differential diagnosis, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Benjamin P.M. Gummlich A , Philipp Ströbel B , Ali Seif Amir Hosseini B , Albrecht Neesse D , Volker Ellenrieder D , Harald Schwörer A*DOI: 10.12659/AJCR.930729
Am J Case Rep 2021; 22:e930729
Figure 2. Magnetic resonance cholangiopancreatography (MRCP) and magnetic resonance imaging (MRI) studies at different times during treatment of immunoglobulin G4-related disease. (A1–A3: on admission, B1–B3: after 6 weeks, C1–C3: after 5 months of treatment). A1 MRCP shows initial intrahepatic and extrahepatic biliary tree dilatation on admission (before treatment) (also see Figure 1A). B1 After 6 weeks of the steroid therapy, MRI reveals total resolution of the subhepatic common bile duct (CBD) stenosis. C1 shows a progressive CBD stenosis with dilated intrahepatic bile ducts after short discontinuation of prednisolone, about 5 months after the start of treatment. A2, B2, C2 (axial T1-weighted) and A3, B3, C3 (axial T2-weighted): In the follow-up examinations after 6 weeks (B2, B3) and 5 months later after steroid therapy (C2, C3), the pancreas appears normal-size, with resolution of the previously seen low-attenuation halo, although a high T2 signal and delayed enhancement of the parenchyma were still detectable on MRI.