Figure 3. (A–D). Secondary captures from a hepatobiliary scan following the IV administration of 8.4 mCi Tc99m mebrofenin. (A) The immediate image demonstrates blood flow and expected hepatic uptake. (B) The 20-minute image demonstrates persistent blood pool activity beyond 15 minutes, best seen within the heart (arrow) and iliac vessels (arrowhead). (C) The gallbladder is visualized prior to 60 minutes on the 40-minute image. (D) The 90-minute image shows small bowel activity. In the absence of a high-grade obstruction, the persistent blood pool activity is suggestive of hepatocellular dysfunction.