Cardiac Amyloidosis Presenting with Pre-Excitation Syndrome, Heart Failure, and Severe Factor X Deficiency as Part of Systemic Amyloid Light-Chain (AL) Amyloidosis – A Fatal Combination

Hussam Almasri; Ahmed Almeer; Samah Awouda; Omnia Hamid; Sundus Sardar; Zubair Anwer; Feryal Ibrahim; Dina Soliman; Yahya Kandathil; Mohammad Abu-Tineh; Imad Alabdul Razzak; Safaa Hasan Alazawi

doi:10.12659/AJCR.933398

19 August 2021: Articles

Cardiac Amyloidosis Presenting with Pre-Excitation Syndrome, Heart Failure, and Severe Factor X Deficiency as Part of Systemic Amyloid Light-Chain (AL) Amyloidosis – A Fatal Combination

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Educational Purpose (only if useful for a systematic review or synthesis)

Hussam Almasri ^A* , Ahmed Almeer ^D , Samah Awouda ^E , Omnia Hamid ^E , Sundus Sardar ^E , Zubair Anwer ^A , Feryal Ibrahim ^B , Dina Soliman ^E , Yahya Kandathil ^A , Mohammad Abu-Tineh ^A , Imad Alabdul Razzak ^E , Safaa Hasan Alazawi ^F

DOI: 10.12659/AJCR.933398

Am J Case Rep 2021; 22:e933398

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Background Case Report Discussion Conclusions References:

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Figure 4. BM biopsy. (A) Amyloid deposits stain pink to red by Congo red by standard light microscopy. (B) The amyloid gives an apple green birefringence under polarized light. (C) (H&E stain), showed a deposition of pink amorphous, waxy-looking deposit, in the thickened blood vessels wall (×500). (D) The deposit is positive for PAS stain (×500).

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Cardiac Amyloidosis Presenting with Pre-Excitation Syndrome, Heart Failure, and Severe Factor X Deficiency as Part of Systemic Amyloid Light-Chain (AL) Amyloidosis – A Fatal Combination

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