Figure 3. Photomicrographs of parotid mass incisional biopsy with hematoxylin and eosin staining, supporting the diagnosis of extramedullary plasmacytoma. (A) Slides of skin and underlying soft tissue (left) show an infiltrative, dense, monotonous, population of large atypical lymphoid cells (right) under 4× magnification. (B) At 40× magnification, large, atypical, lymphoid cells with open chromatin, prominent nucleoli, and moderate amount of pale blue cytoplasm are seen. Both plasmacytic (white arrow) and plasmablastic morphology (white star) are noted in these atypical cells with eccentric nuclei. Frequent mitotic figures are also noted (black arrows).