Figure 2. Representative skin lesions and histological findings of bullous pemphigoid on skin biopsy. (A) Multiple vesicular and tense bullae lesions over the upper arm presented on admission. (B) Hematoxylin and eosin staining of skin biopsy showed eosinophilic spongiosis, subepidermal cleft and mixed dermal inflammation with numerous eosinophils and neutrophils (magnification: 400×). (C) Direct immunofluorescence staining of skin biopsy revealed strong deposition of linear complement 3 along the basement membrane zones (magnification: 400×).