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04 March 2024: Articles

A Rare Case of Non-IgM Lymphoplasmacytic Lymphoma with Unusual Lack of Immunoglobulin Light Chain Production

Challenging differential diagnosis, Rare disease

Jiejing Yin C , Ashish Bains C , Mohamed Alsammak E , Jian Jeff Fu A*

DOI: 10.12659/AJCR.940963

Am J Case Rep 2024; 25:e940963

Figure 4. Bone marrow showing involvement by lymphoplasmacytic lymphoma. In situ hybridization for kappa (A) and lambda (B) demonstrating lack of light chain expression by neoplastic infiltrate. Immunohistochemistry highlighting the neoplastic plasma cell that express IgA (C), while lacking IgM (D).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923