04 December 2023: Articles
A Case Report of a Rare ER+, PR- Pure Metaplastic Breast Squamous Cell Carcinoma with HER2 Overexpression
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease
Shafawati Akmal Adam A , Khairatul Nainey Kamaruddin E , Nordashima Abdul Shukor B , Shahrun Niza Abdullah Suhaimi C , Fuad Ismail C , Mazapuspavina Md Yasin A*DOI: 10.12659/AJCR.941448
Am J Case Rep 2023; 24:e941448
Figure 2. (A, B) Immunohistochemistry (IHC) of the cyst wall curettage. (A) IHC shows that malignant cells are positive for estrogen receptors with 40% positivity of moderate to strong intensity. (B) IHC shows strong expression (3+) for erythroblastic oncogene B-2 (c-erb-B2). (400× magnification) Progesterone receptor: negative.