05 December 2023: Articles
A Rare Skin Rash: Linezolid-Induced Purpuric Drug Eruption without Vasculitis in a Hispanic Male
Challenging differential diagnosis, Adverse events of drug therapy
Marilee A. Tirú-Vega A* , Natalie Engel-Rodriguez B , Nicole Rivera-Bobé B , Carla N. Cruz-Díaz DDOI: 10.12659/AJCR.941725
Am J Case Rep 2023; 24:e941725
Figure 2. Photomicrographs of a skin punch biopsy from the purpuric rash of the abdominal wall in an 89-year-old man with linezolid-induced purpuric drug eruption. (A) The skin biopsy shows a superficial and perivascular interstitial infiltrate of lymphocyte and eosinophil polymorphs infiltrating dermal capillaries and venules. Hematoxylin and eosin (H&E); magnification 100×. (B) Closeup of the skin biopsy shows predominance of eosinophils in the perivascular infiltrate. H&E; magnification 400×.