Unusual clinical course
Aruna S. Kumari
CaseRepClinPractRev 2004; 5:462-464
Available online: 2004-04-20
Background: The risk of an SLE mother with anti-Ro and anti-La antibodies having an infant with NLE and CCHB is between 1-2 %. The risk of having recurrent NLE is even lower. We report a
case of a 32-year-old woman with SLE who had two successive pregnancies with CCHB.Case Report: A 32-year-old woman, a known case of SLE was strongly positive for anti Ro antibodies. CCHB was diagnosed at 16-18 weeks in both the pregnancies and treated with steroids without any success. The first baby succumbed due to full blown NLE, the second one needed a pacemaker.Conclusions: It is probably reasonable to administer corticosteroids starting early in pregnancy in Ro positive women with prior history of NLE.
Keywords: Systemic lupus erythematosus (SLE), Neonatal lupus erythematosus (NLE), Complete CongenitalHeart block (CCHB)