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Insulin Resistant Diabetes Mellitus in Systemic Lupus Erythematosus

Isabella Vargas de Souza Lima, Liliana D’Almeida Galrão, Bárbara Oliveira, Fernando Edington, Mittermayer Barreto Santiago

CaseRepClinPractRev 2005; 6:203-206

ID: 428473

Available online:


Background: Systemic lupus erythematosus (SLE) is a multi-systemic disease of autoimmune nature. Diabetes
mellitus (DM) is commonly seen in SLE patients particularly secondary to corticosteroid therapy.
Case Report: We report a case of a 33-year-old black female patient who developed SLE and severe insulin
resistant diabetes mellitus. She also had other features of the type B syndrome of insulin resistance
as skin hyperpigmentation, age of onset of the diabetes, race and sex.
Conclusions: The present report is the first case of SLE with such complication described in Brazil. A literature review on this subject is shown.

Keywords: systemic lupus erythematosus, Diabetes Mellitus, Autoantibodies