Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 October 2005

Interstitial lung disease and neuropathy as predominant extra-articular manifestations in patients with rheumatoid arthritis: a prospective study.

Anurag Bharadwaj, Nigil Haroon

Med Sci Monit 2005; 11(10): CR498-502 :: ID: 430312

Abstract

BACKGROUND: Rheumatoid arthritis (RA) patients with extra-articular manifestations(ExRA) have a severe course of the disease and higher mortality. Indian patients are considered to havea low prevalence of ExRA. We prospectively assessed ExRA in patients with rheumatoid arthritis from southernIndia. MATERIAL/METHODS: 140 RA patients were qualified for the study. Patients with confounding factorswere excluded. A detailed history and clinical examination was performed. Two independent investigatorsmade a thorough search with relevant investigations for ExRA, according to well-defined criteria. RESULTS:At least one ExRA was present in 36 patients (25.7%). The predominant ExRA (9.29%) was Interstitial LungDisease (ILD). 12 patients had neuropathy (8.57%). 5 patients had eye involvement, while 3 had cutaneousvasculitis. 4 patients had rheumatoid nodules, and 1 had amyloidosis. The median age at diagnosis andduration of disease were significantly higher in patients with ExRAs than in those without. Deformitiesand the use of steroids were more common in the ExRA cohort. CONCLUSIONS: The present study shows a highprevalence of ILD and neuropathy as ExRAs in our population. A more extensive investigative protocolis warranted for picking up milder presentations of these serious manifestations.

Keywords: Arthritis, Rheumatoid - physiopathology, Confounding Factors (Epidemiology), Joint Diseases - physiopathology, Lung Diseases, Interstitial - physiopathology, Peripheral Nervous System Diseases - physiopathology, Prospective Studies

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

18 Mar 2024 : Clinical Research  

Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative Study

Med Sci Monit In Press; DOI: 10.12659/MSM.944136  

0:00

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750