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Medical Science Monitor Basic Research


Dyspnea in a patient with aortic aneurysm history: initial manifestation of Takayasu arteritis

Lampros Raptis, Georgios Pappas, Georgios Passas, Konstantinos Bugias, Violeta Maltabe, Nikolaos Akritidis

CaseRepClinPractRev 2006; 7:170-173

ID: 452943

Available online:


Background: Pulmonary arteries’ involvement is well described in Takayasu’s arteritis, a condition that is
mainly associated with involvement of the systemic arteries.
Case Report: The purpose of this article is to report a case of a 73-year-old woman, who presented with
increasing exertional dyspnea, caused by pulmonary artery involvement in Takayasu’s arteritis,as shown by narrowing of the right pulmonary artery in digital angiography. The diagnosis was set by clinical and angiographic findings as proposed by The American College of Rheumatology(ACR). The patient was treated with immunosuppressive therapy with improvement in both diagnostic imaging and laboratory findings. The patient reported a history of aortic aneurysm in her youth, probably associated with Takayasu arteritis, but the latter remained unrecognised until pulmonary involvement became symptomatic.
Conclusions: In literature review, only a few cases of Takayasu disease have been reported with dyspnea as
initial manifestation. Awareness of this unusual presentation may augment in rapid orientation
of differential diagnosis and proper early treatment.

Keywords: Dyspnea, Pulmonary Artery, Takayasu, Vasculitis