01 March 2001
Immunosuppressive treatment after liver transplantation
Urszula Ołdakowska-Jedynak, Leszek Pączek, Marek Krawczyk, Bogdan Michałowicz, Piotr Małkowski, Jacek Pawlak, Paweł NyckowskiCase Rep Clin Pract Rev 2001; 2(3):244-253 :: ID: 475248
Abstract
Significant improvement of the results of liver transplantations is due not only to better surgical techniques, but also to a considerable progress in the field of immunosuppressive treatment. The currently used preparations present a wide spectrum of possibilities for suppression of the liver graft recipient's immune system. They also make it possible to apply the optimum immunosuppression protocol after OLT. The paper is not only a review of immunosuppressive treatment methods used after OLT all over the world, but it is also focused on the discussion of practical, pharmacological aspects of such treatment, taking into consideration the characteristics of individual preparations and, which is very important, their side effects and mutual interactions. In our opinion, effective suppression of the recipient's immune system used to prevent acute rejection processes, taking into account not only the immunosuppressive potential of the drug but also its, usually narrow therapeutic 'window' resulting in its toxicity and side effects, as well as subsequent intensive immunosuppressive treatment, are the prerequisites for safe management of patients after liver transplantations. Therefore, discussion of the most important aspects of post-OLT immunosuppressive treatment becomes extremely important in view of current advances in Polish liver transplantology.
Keywords: Immunosuppression, Liver Transplantation
27
In Press
06 Mar 2024 : Case report
Successful Healing of Periapical Pathology with Partial Pulpotomy in a Mature Permanent Molar: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.942937
12 Mar 2024 : Case report
Successful Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus with Celecoxib: A Promising Therapeu...Am J Case Rep In Press; DOI: 10.12659/AJCR.943244
13 Mar 2024 : Case report
Recurrent Marginal Zone Lymphoma with Bone Marrow Involvement Detected by ¹⁸F-FDG PET/CT and Biopsy: A Diag...Am J Case Rep In Press; DOI: 10.12659/AJCR.943275
13 Mar 2024 : Case report
Unveiling the Temporal Aspect of MRI Tattoo Reactions: A Prospective Evaluation of a Newly-Acquired Tattoo ...Am J Case Rep In Press; DOI: 10.12659/AJCR.943411
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250