01 January 1998
Congenital chloride diarrhea - case from Poznań (Western Poland)
Krzysztof Borski, Danuta Kostrzewa-Szymic, Jarosław Walkowiak, Marian KrawczyńskiMed Sci Monit 1998; 4(1): CS165-168 :: ID: 502852
Abstract
Congenital chloride diarrhea (CCD) is a rare autosomal recessive disease characterized by persistent watery diarrhea with high faecal Cl- concentration. It results from a defect in the HCO3/Cl- exchange in the distal ileum and colon. This defect leads to impaired Cl- and Na+ absorption. Hydramnios, premature birth, no passage of meconium and distended intestine are typical features of CCD in the neonate, and severe metabolic alkalosis, hypochloraemia, hypokalaemia and retarded growth and development are common symptoms. Plasma renin and aldosterone concentration could be highly elevated and renal abnormalities could develop.The treatment of CCD is based on full oral replacement of faecal losses of Cl-, Na+, K+, and water. A girl one and a half year old with CCD has been treated in our clinic with good follow up: normal electrolytes and gasometric parameters, normal renal function and good growth and psychomotor development are reported.
Keywords: in-born error of metabolism, Congenital chloride diarrhea
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
06 Mar 2024 : Clinical Research
Comparison of Outcomes between Single-Level and Double-Level Corpectomy in Thoracolumbar Reconstruction: A ...Med Sci Monit In Press; DOI: 10.12659/MSM.943797
21 Mar 2024 : Meta-Analysis
Economic Evaluation of COVID-19 Screening Tests and Surveillance Strategies in Low-Income, Middle-Income, a...Med Sci Monit In Press; DOI: 10.12659/MSM.943863
10 Apr 2024 : Clinical Research
Predicting Acute Cardiovascular Complications in COVID-19: Insights from a Specialized Cardiac Referral Dep...Med Sci Monit In Press; DOI: 10.12659/MSM.942612
06 Mar 2024 : Clinical Research
Enhanced Surgical Outcomes of Popliteal Cyst Excision: A Retrospective Study Comparing Arthroscopic Debride...Med Sci Monit In Press; DOI: 10.12659/MSM.941102
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952