03 March 2008
Goblet cell carcinoid of the appendix: report of a case and review of the literature
Salman Yousuf GurayaAm J Case Rep 2008; 9:140-143 :: ID: 843052
Abstract
Background: Goblet cell carcinoid (GCC) is an extremely rare tumor of the appendix that demonstrates a wide range of atypical presentations masquerading acute appendicitis. GCC exhibits variable malignant potential and shares the histological features of both carcinoids and adenocarcinoma. These tumors are never diagnosed pre operatively and require a high index of suspicion during the histological, histochemical and immunohistochemical analysis.
Case Report: This case report describes a 54-year-old lady presented to the emergency room with the clinical impression of acute appendicitis. She subsequently underwent an uneventful laparoscopic appendectomy. The histological examination of the specimen reported a well differentiated GCC of the appendix with no cecal infiltration. The post operative imaging was unremarkable whereas the serum chromogranin A level was found to be high. The patient received six cycles of 5-FU and leucovorin and remained well during the follow up.
Conclusions: Although GCC is rare, this should be a diagnostic consideration in suspected appendicitis, especially in old age. Appendectomy is the treatment of choice for low grade tumors localized to the appendix.
Keywords: Chromogranin A, goblet cell carcinoid
In Press
16 Mar 2024 : Case report
Early Diagnosis and Successful Empirical Treatment of L1-L2 Spondylodiscitis in a 21-Month-Old Girl: A Case...Am J Case Rep In Press; DOI: 10.12659/AJCR.943010
16 Mar 2024 : Case report
A Rare Autochthonous Case of Hepatic Hydatid Cyst in the Non-Endemic Region of TaiwanAm J Case Rep In Press; DOI: 10.12659/AJCR.943687
17 Mar 2024 : Case report
Contrast-Enhanced Ultrasonography in Diagnosing Intravascular Large B-Cell Lymphoma Infiltrating Liver Sinu...Am J Case Rep In Press; DOI: 10.12659/AJCR.943070
17 Mar 2024 : Case report
Rare Presentation of Rapidly Involuting Congenital Hemangioma of the Skull: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.943370
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250