13 November 2009
Am J Case Rep 2009; 10:189-192 :: ID: 878250
Background: Squamous cell carcinoma (SCC) is a rare and unusual cancer. Pancreatic malignancies can be classified into endocrine and non-endocrine tumors. Of the non-endocrine tumors, ductal carcinoma is the most common, and the ductal carcinomas can be further subdivided into adenocarcinomas and SCCs.
Case Report: In a 51-year-old man presenting with stomach fullness and abdominal pain, a computed tomography (CT) scan identified a 4-cm mass in the tail of pancreas. Combined positron-emission tomography–CT revealed a donut-shaped hypermetabolic abnormality in the pancreatic tail consistent with a primary malignant neoplasm featuring central necrosis. The diagnosis of pancreatic SCC was entertained after biopsy of a metastatic lesion in close proximity to the primary tumor. A diagnosis of adenosquamous carcinoma could not be ruled out, but the close proximity of a metastatic lesion to the primary tumor and negative tumor markers was more suggestive for SCC.
Conclusions: Most SCC tumors are advanced at presentation. Clear guidelines for the management of this rare malignancy are lacking, and the response of this histologic type of pancreatic cancer to chemoradiation is not encouraging. The disease is aggressive, and the outcome is typically dismal.
Keywords: pancreatic cancer, Pancreas, squamous cell carcinoma
19 May 2022 : Case reportBilateral Emphysematous Pyelonephritis Associated with COVID Pneumonia: A Case Report
Am J Case Rep In Press; DOI: 10.12659/AJCR.936370
17 May 2022 : Case reportHigh-Frequency Oscillatory Ventilation for Refractory Hypoxemia in Severe COVID-19 Pneumonia: A Small Case ...
Am J Case Rep In Press; DOI: 10.12659/AJCR.936651
13 May 2022 : Case reportA case of exacerbation of haloperidol-induced rhabdomyolysis following the onset of COVID-19
Am J Case Rep In Press; DOI: 10.12659/AJCR.936589
20 May 2022 : Case reportDiagnostic Puzzle of Acute Ischemic Stroke Mimics – Seizure Versus Post-Stroke Recrudescence: A Case Report
Am J Case Rep In Press; DOI: 10.12659/AJCR.936826
19 May 2022 : Case reportExtremes of Anemia: The Lowest Hemoglobin Values Probably Ever Reported in the Pediatric Literature Attribu...
Am J Case Rep In Press; DOI: 10.12659/AJCR.936252
19 May 2022 : Case reportAcute Hepatitis with Positive Autoantibodies: A Case of Natalizumab-Induced Early-Onset Liver Injury
Am J Case Rep In Press; DOI: 10.12659/AJCR.936318
Most Viewed Current Articles
31 Dec 1969 : Case reportPenile Necrosis Associated with Local Intravenous Injection of Cocaine
Am J Case Rep 2022; 23:e935250
31 Dec 1969 : Case reportMyocarditis, Pulmonary Hemorrhage, and Extensive Myositis with Rhabdomyolysis 12 Days After First Dose of P...
Am J Case Rep 2022; 23:e934399
31 Dec 1969 : Case reportLipedema Can Be Treated Non-Surgically: A Report of 5 Cases
Am J Case Rep 2021; 22:e934406