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Acquired lymphangioma circumscriptum of the vulva secondary to radiotherapy

Bulent Akansu, Esin Atik, Suleyman Altintas, Gamze Serarslan, Kenan Dolapcioglu, M. Serefettin Canda

Am J Case Rep 2010; 11:5-6

ID: 878325

Published: 2010-01-08

Background: Lymphangioma circumscriptum is a benign lesion of the lymphatics. The primary form of the disease is generally seen at birth or during childhood, whereas the secondary (acquired) form is a result of radiotherapy or a surgical procedure.
Case Reoprt: A 38-year-old female patient was admitted to hospital with the complaint of skin eruptions on her vulva. About 10 years before she had had a total abdominal hysterectomy and bilateral salpingooophorectomy because of squamous cell carcinoma of the cervix and radiotherapy had been performed to the perineal region after surgery. Papillary-like lesions on the skin were seen in gross examination. These lesions were diagnosed as acquired lymphangioma circumscriptum by microscopy.
Conclusions: Acquired lymphangioma is a benign lesion which can appear many years after radiotherapy. Several pre-malignant and malignant lesions can also occur following radiotherapy in this region. Therefore it is important for the clinician and pathologist to be aware of this situation and be careful when making the differential diagnosis.

Keywords: Radiotherapy, lymphangioma, vulval disease