Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

19 January 2010

Unusual case of Burkitt lymphoma with thyroid gland and abdominal involvement

Jaspreet S Grewal, Naresh T Gunaratnam, John C Krauss, Lauren B Smith

Am J Case Rep 2010; 11:16-19 :: ID: 878329

Abstract

Background: Burkitt lymphoma (BL) is a high grade, diffuse, small non-cleaved B-cell non-Hodgkin lymphoma (NHL). Endemic BL occurs in equatorial Africa and involves the jaw and facial bones in young children. Sporadic BL occurs in rest of the world and frequently presents as an abdominal mass. Sporadic BL rarely involves the head and neck region. BL involving the thyroid gland is rare and has never been reported with pancreatic and small intestinal involvement and associated pancreatitis.
Case Report: An unusual case of a 31-year-old male from India is reported who was diagnosed with Stage IV BL involving the thyroid gland, pancreas and the small intestines (jejunum and ileum). Morphologic evaluation of the open thyroid biopsy and endoscopic ultrasound guided (EUS) pancreatic needle aspirate was consistent with BL. The diagnosis was confirmed with immunohistochemistry (IHC), flow cytometry and fluorescence-in-situ-hybridization (FISH). The patient was successfully treated with CODOX-M/IVAC chemotherapy regimen in combination with rituximab and is in remission two years after the completion of the treatment.
Conclusions: Our patient presented with a very unusual clinical presentation of BL involving the thyroid gland and multiple abdominal organs. Morphologic evaluation of the tissue biopsy should be complemented with IHC, flow cytometry and FISH, and guided by 2008 World Health Organization (WHO) Classification of Tumors of Hematopoietic and Lymphoid Tissues to confirm the diagnosis. Complete remission in patients with BL presenting with multiple organ involvement can be achieved with aggressive chemotherapy.

Keywords: Burkitt Lymphoma, Thyroid gland, Pancreas, Pancreatitis, small intestine, non-Hodgkin lymphoma

0 Comments

SARS-CoV-2/COVID-19

18 January 2022 : Case report  Italy

Sickle Cell Trait and SARS-CoV-2-Induced Rhabdomyolysis: A Case Report

Am J Case Rep In Press; DOI: 10.12659/AJCR.934220  

11 January 2022 : Case report  Oman

Myocarditis, Pulmonary Hemorrhage, and Extensive Myositis with Rhabdomyolysis 12 Days After First Dose of P...

Am J Case Rep In Press; DOI: 10.12659/AJCR.934399  

12 January 2022 : Case report  USA

Guillain-Barré Syndrome After Ad26.COV2.S Vaccination

Am J Case Rep In Press; DOI: 10.12659/AJCR.935275  

10 January 2022 : Case report  Philippines

Pulmonary Function and Chest Computed Tomography (CT) Scan Findings After Antifibrotic Treatment for COVID-...

Am J Case Rep In Press; DOI: 10.12659/AJCR.934830  

In Press

19 Jan 2022 : Case report  Latvia

Rare Case of Hodgkin Lymphoma Transformation into Diffuse Large B-Cell Lymphoma with Atypical Spread Epidur...

Am J Case Rep In Press; DOI: 10.12659/AJCR.935014  

19 Jan 2022 : Case report  Saudi Arabia

Autoimmune Hemolytic Anemia – Rare Complication of Brucellosis in a Saudi Woman: A Case Report and Literatu...

Am J Case Rep In Press; DOI: 10.12659/AJCR.935187  

18 Jan 2022 : Case report  Saudi Arabia

Annular Epidermolytic Ichthyosis Mimicking Greither Disease: A Case Report and Literature Review

Am J Case Rep In Press; DOI: 10.12659/AJCR.935393  

18 Jan 2022 : Case report  USA

Penile Necrosis Associated with Local Intravenous Injection of Cocaine

Am J Case Rep In Press; DOI: 10.12659/AJCR.935250  

Most Viewed Current Articles

10 Jan 2022 : Case report  Germany

A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...

DOI :10.12659/AJCR.935263

Am J Case Rep 2022; 23:e935263

06 Dec 2021 : Case report  Brazil

Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

DOI :10.12659/AJCR.934406

Am J Case Rep 2021; 22:e934406

24 Jul 2020 : Case report  Canada

Symptoms of Pleurisy as the Initial Presentation of COVID-19

DOI :10.12659/AJCR.925775

Am J Case Rep 2020; 21:e925775

09 Dec 2021 : Case report  USA

Left Ventricular Assist Device Pump Thrombosis in a Patient Treated with Apixaban

DOI :10.12659/AJCR.934787

Am J Case Rep 2021; 22:e934787

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923