22 October 2010
Autoimmune pancreatitis masquerading as distal cholangiocarcinoma: A case series of two cases
Rebecca S. Lewis, Haris A. Khwaja, Andrew Wotherspoon, Jeremy N. Thompson, Aamir Z. KhanAm J Case Rep 2010; 11:182-185 :: ID: 881209
Abstract
Background: Autoimmune pancreatitis (AIP) is a rare but distinct form of the disease with manifestations both within the pancreas and outside. Autoimmune pancreatitis can present with extrahepatic strictures which can be difficult to distinguish from malignant strictures, including cholangiocarcinoma. Elevated serum IgG4 levels are a feature of autoimmune pancreatitis and histologically the disease is characterised by a significant periductal lymphoplasmacytic infiltration rich in IgG4 positive cells.
Case Report: The following two cases represent the different treatment options available to patients presenting with malignant bile duct strictures thought to be cholangiocarcinoma which eventually proved to be due to autoimmune pancreatitis. Patient 1 is a 62 year old gentleman of South American descent, and patient 2 is a 72 year old Caucasian gentleman.
Conclusions: Pre-operative diagnosis in autoimmune-related bile duct strictures is important as it may negate the need for major complex surgery.
Keywords: autoimmune pancreatitis, Cholangiocarcinoma, pancreatic cancer
In Press
12 Feb 2024 : Case report
Diagnostic Challenges and Imaging Considerations for Intraparotid Facial Nerve Schwannoma: A Case Report an...Am J Case Rep In Press; DOI: 10.12659/AJCR.942870
12 Feb 2024 : Case report
Erdheim-Chester Disease Occult on Radiographs and CT but Visible on MRI and PETAm J Case Rep In Press; DOI: 10.12659/AJCR.941169
12 Feb 2024 : Case report
Surgical Treatment of Spontaneous Superficial Temporal Artery Arteriovenous Malformation: A Case ReportAm J Case Rep In Press; DOI: 10.12659/AJCR.942839
13 Feb 2024 : Case report
Warfarin Woes: A Rare Case of Hemoperitoneum with Intramural Small Bowel HematomaAm J Case Rep In Press; DOI: 10.12659/AJCR.943519
Most Viewed Current Articles
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
05 Mar 2022 : Case report
Acute Limb Ischemia After Self-Injection of Crushed Morphine Tablets into the Radial Artery: Role of Infrar...DOI :10.12659/AJCR.935336
Am J Case Rep 2022; 23:e935336
02 Apr 2022 : Case report
Infective Endocarditis Caused by Pseudomonas luteola in a Pediatric Patient. A Case Report and Review of Li...DOI :10.12659/AJCR.935743
Am J Case Rep 2022; 23:e935743