Xutao Miao, Bengang Peng, Xin Wang, Lihua Gong
Am J Case Rep 2010; 11:248-251
Background: Giant cell tumor of tendon sheath (GCTTS) is a benign, solitary lesion, which is relatively common in the hand. It can also be found around the palm, hip, foot, ankle or knee joint, while lesions in the head and neck are very rare, especially in the nose. Here we present an unusual case of giant cell tumor of tendon sheath in the nasal root, which may be the first report in this site.
Case Report: A 65-year-old patient had a medical history of masses in the hands for more than 20 years, and lesions in the nasal root for 2 years. Prior operations and pathology report proved the diagnosis of GCTTS in the hands. The patient denied a history of trauma and familial heritable diseases. An operation were done to remove the masses in the nasal root and hands, and pathology demonstrated sign of GCTTS. At 2.5 years follow-up, there was no recurrence in the nasal root, but the lesions in the hand had recurred.
Conclusions: This case indicates that, except for the hands, GCTTS can occur in other sites; the nasal root is the newest site reported in the literature. GCTTS has the character of soft tissue, total excision is needed to avoid the recurrence, and radiotherapy may be helpful in some cases.
Keywords: tendon sheath, Nose Neoplasms, giant cell tumour, therapy