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Medical Science Monitor Basic Research


Ecthyma gangrenosum in a previously healthy pediatric patient and associated facial paralysis and persistent hyperplastic primary vitreous

Ibrahim Hakan Bucak, Gökhan Tümgör, Eda Mengen, Fatih Temiz, Mehmet Turgut

Am J Case Rep 2012; 13:250-253

DOI: 10.12659/AJCR.883503

Available online:

Published: 2012-10-15


Background:    Ecthyma gangrenosum is an infective lesion of the skin and mucosal membranes. It is most commonly caused by Pseudomonas aeruginosa, and the most important risk factors are malignancy and neutropenia. However, it has rarely been reported in children who were previously healthy. Persistent hyperplastic primary vitreous has been described as the persistence of the fetal hyaloid vascular system. Acute otitis media with facial paralysis is an infrequent association.
    Case Report:    We report the case of a 5-month-old boy hospitalized because of fever, otorrhea and necrosis on his body. He had peripheral facial paralysis on the same side as otorrhea. Leukocoria was determined in the right eye. He had many gangrenous ulcers on the extremities and body.
    Conclusions:    We present a previously healthy pediatric patient diagnosed with persistent hyperplastic primary vitreous, ecthyma gangrenosum (by the septicemia of P. aeruginosa), and peripheric facial paralysis (a complication of acute otitis media), admitted to hospital.

Keywords: ecthyma gangrenosum, Facial Paralysis, pseudomonas septicemia, persistent hyperplastic primary vitreous