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Medical Science Monitor Basic Research


A rare cause of hypocalcemia

Islam Y. Elgendy, Timi Rotimi Omokehinde

Am J Case Rep 2013; 14:113-115

DOI: 10.12659/AJCR.883889

Available online: 2013-04-19

Published: 2013-04-19

Background: Many factors influence serum calcium concentration, but the major determinants of calcium homeostatsis are parathyroid hormone (PTH), vitamin D, the ionized calcium, and phosphate [1]. Therefore, deranged calcium metabolism is often seen in the presence of disordered parathyroid hormone (PTH) and/or vitamin D actions. Among these causes is end-organ resistance to the biological effect of parathyroid hormone.
Case Report: In this paper, we report a case of a patient who presented with flu like symptoms and incidental finding of hypocalcemia that is consistent with parathyroid hormone resistance.
Conclusions: Familial causes of hypocalcemia, although rare, should be thought about after ruling out the other common causes of hypocalcemia.

Keywords: Hypocalcemia, hyperphosphatemia, Parathyroid Hormone