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Medical Science Monitor Basic Research


COPE procedure in process: Antiplagiarism Procedure

Squamous cell carcinoma of the breast

Suresh Jaywantrao Bhosale, Ashok Yadavrao Kshirsagar, Sushil Jalindar Deshmukh, Sunil V. Jagtap, Yodesh B. Langade

Am J Case Rep 2013; 14:

DOI: 10.12659/AJCR.883934

Available online: 2013-06-05

Published: 2013-06-05


Background: Primary squamous cell carcinoma (SCC) is a very rare malignancy of the breast. It is a tumour of the elderly age group. Pure squamous cell carcinoma of the breast can deviate from epidermis, the nipple or the epithelium of deep-seated epidermoid cyst or squamous metaplasia on chronic inflammation background.
Case Report: Our case is a 60-year-old female patient who presented with a lump in her left breast. Left-side modified radical mastectomy was done. It was histopathologically diagnosed as squamous cell carcinoma of the breast (SCCB).There was no axillary node involvement. After one and half years, the patient presented with breathlessness and weakness. Investigations revealed lung metastasis with pleural effusion, and postoperative chemotherapy was given. The patient has attended regular follow-ups for the last 8 months.
Conclusions: The prognosis of this disease is highly uncertain and the treatment options are unclear and controversial. There is inadequate literature and treatment guidelines are lacking.

Keywords: squamous cell carcinoma of the breast (SCCB), chemotherapy, modified radical mastectomy