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Medical Science Monitor Basic Research


Simultaneous double coronary thrombosis in a 47-year-old male patient with acute myocardial infarction

Unusual clinical course, Diagnostic / therapeutic accidents, Management of emergency care

Ahmed Mahmoud, Abdul Arabi

USA Department of Internal Medicine, University of Florida, Gainesville, USA

Am J Case Rep 2013; 14:430-434

DOI: 10.12659/AJCR.889556

Available online: 2013-10-23

Published: 2013-10-23


Background: Double myocardial infarction involving two culprit major vessels is a rarely reported presentation with high incidence of mortality.
Case Report: In this study, we report 47-year-old male patient who had an attack of chest pain associated with ST-segment elevation in the antero-lateral leads. Pharmaco-invasive reperfusion approach was adopted with full dose tissue plasminogen activator, followed by transferring the patient to a specialized heart center for Percutaneous Coronary Intervention (PCI). Coronary angiography showed a fresh thrombus totally occluding Left Anterior Descending (LAD) and another thrombus causing distal total occlusion of a dominant Right Coronary Artery (RCA). Two Bare metal stents were placed in both lesions with Thrombolysis in Myocardial Infarction (TIMI) 3 flow post dilatation, but the patient, unfortunately, went into Ventricular Fibrillation (VF) followed by asystole and died 35 minutes later.
Conclusions:  Acute double vessel coronary artery thrombosis is a serious event that requires prompt diagnosis and management to prevent its complications.

Keywords: multiple plaques rupture, double coronary thrombosis, coronary occlusion