17 January 2014
: Case report 
Total hip replacement for an ochronotic patient: A technical trick
Unusual setting of medical care, Rare disease, Congenital defects / diseases, Educational Purpose (only if useful for a systematic review or synthesis)
Oguz CebesoyA, Mustafa IsikB, Mehmet SubasiD, Abbas KayaE, Fethi BilginF, Oğuz KayaFDOI: 10.12659/AJCR.890008
Am J Case Rep 2014; 15:27-30
Abstract
Background: Ochronosis is an inherited metabolic disease in which there is an accumulation of excessive amounts of homogentisic acid in the connective tissue. As the disease progresses, the chronic inflammation in the damaged tissue can cause degeneration and osteoarthritis. There is no specific treatment for ochronosis because it is a rare disease and arthroplasty is seldom performed.
Case Report: We report the case of a 46-year-old male patient with ochronosis, who underwent an arthroplasty of the right hip due to osteoarthritis. The problems encountered during surgery are reported and discussed.
Conclusions: Arthroplasty is a highly effective procedure for ochronotic patients. Particular attention to the surgical step is highly advised.
Keywords: Alkaptonuria, Ochronosis, Orthopedic Procedures, Arthroplasty, Replacement, Hip, Arthroplasty
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