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01 February 2014 : Case report  China (mainland)

Total parenteral nutrition caused Wernicke’s encephalopathy accompanied by wet beriberi

Unusual clinical course, Mistake in diagnosis, Diagnostic / therapeutic accidents

Ling LongBE, Xiao-Dong CaiBE, Jian BaoCD, Ai-Min WuCD, Qing TianF, Zheng-Qi LuA

DOI: 10.12659/AJCR.890041

Am J Case Rep 2014; 15:52-55

Abstract

Background: Wernicke’s encephalopathy (WE) is an acute and life-threatening illness which is not only seen in alcoholics, but also in persons with poor nutrition lacking thiamine (vitamin B1).
Case Report: Here, we presented a case of WE in a patient who received parenteral nutrition without complement of thiamine. Besides neuropsychiatric problems, she also manifested prominent cardiovascular abnormalities, which were consistent with wet beriberi.
Conclusions: This case emphasizes the need for thiamine supplementation in prolonged total parenteral nutrition, and also highlights the awareness of WE in persons with parenteral nutrition lacking thiamine. More importantly, we call for attention to wet beriberi in such persons.

Keywords: Parenteral Nutrition, Total - adverse effects, Thiamine Deficiency, Beriberi, Wernicke Encephalopathy

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923