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Medical Science Monitor Basic Research


Storiform-Pleomorphic Type of Multifocal Malignant Fibrous Histiocytoma of the Lumbar Spine

Challenging differential diagnosis, Unusual setting of medical care, Rare disease

Aykut Akpinar, Cengiz Omer Ozdemir, Necati Ucler, Haci Mehmet Inan

Turkey Department of Neurosurgery, Adiyaman University Education and Research Hospital, Adiyaman, Turkey

Am J Case Rep 2014; 15:565-568

DOI: 10.12659/AJCR.891290

Available online:

Published: 2014-12-21


Background: We present the extremely rare case of a 67-year-old male with malignant fibrous histiocytoma, arising in the lumbar spine, demonstrated with radiological and pathological studies.
Case Report: The patient and his relatives refused open surgical approach and we performed transpedicular vertebral corpus biopsy and vertebroplasty under spinal anesthesia. His pathological result was malignant fibrous histiocytoma. The spine is a very uncommon site for malignant fibrous histiocytoma.
Conclusions: The management of malignant fibrous histiocytoma relies on the combination of maximum decompression surgery, chemotherapy and radiotherapy. Total removal is unrealistic and diagnosis is difficult. The prognosis in terms of continuing neurological deficit after surgery appears to be poor.

Keywords: Histiocytoma, Malignant Fibrous - surgery, Lumbar Vertebrae, Spinal Neoplasms - surgery