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Medical Science Monitor Basic Research


Resolution of an Acute Aortic Syndrome with Aortic Valve Insufficiency Post-PCI

Unusual clinical course, Unusual setting of medical care

Pedro G.M. de Barros e Silva, Thiago Aquino, Marcos V. Resende, Ivo Richter, Cecilia M. Barros, Vanessa G. Andrioli, Antonio C. Baruzzi, Caio C.J. Medeiros, Valter Furlan

Brazil Department of Clinical Research, Hospital Totalcor, Sao Paulo, Brazil

Am J Case Rep 2014; 15:508-513

DOI: 10.12659/AJCR.891301

Available online:

Published: 2014-11-21


Background: Acute aortic syndrome is the modern term that includes aortic dissection, intramural hematoma, and symptomatic aortic ulcer. Iatrogenic coronary artery dissection extending to the aorta during percutaneous coronary intervention is a very rare but life-threatening complication. Despite some reports of spontaneous recovery, most of these patients are treated surgically as a spontaneous aortic dissection, especially if there is a complication of the aortic lesion.
Case Report: A 52-year-old white female was submitted to an angioplasty in the right coronary without success and the procedure was complicated by a dissection in aortic root with progressive extension to the ascending aorta. This lesion deformed the aortic valve, leaving it with an acute moderate regurgitation. Because of current use of clopidogrel and clinical stability of the patient, the local Heart Team decided to withdrawn this antiplatelet for 5 days before surgery despite the risk related to the aortic syndrome. A new echocardiogram 3 days later showed that the hematoma was reabsorbed with improvement of the aortic insufficiency. An angiotomography confirmed the reabsorption of the hematoma. The surgery was canceled and the patient was maintained in a conservative treatment and discharged. Seventeen months later, she was re-evaluated and was still asymptomatic without aortic regurgitation in the echocardiogram and showing progressive regression of the aortic hematoma in the tomography.

Conclusions: Despite the conservative treatment, this case of iatrogenic aortic dissection complicated by an acute aortic regurgitation had a good evolution in a follow-up of 17 months.

Keywords: Acute Coronary Syndrome - surgery, Acute Disease, Aneurysm, Dissecting - etiology, Aortic Aneurysm, Thoracic - etiology, Aortic Valve Insufficiency - diagnosis, Coronary Angiography, Echocardiography, Transesophageal, Percutaneous Coronary Intervention - adverse effects, Remission, Spontaneous, Syndrome, Tomography, X-Ray Computed