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Inhibition of SA Node at Supine Position in Right Atrial Thrombus Complicating Behçet’s Disease – From Cardiac Surgical Point of View

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Emad Mohamed Hijazi, Rasheed Khaled Ibdah, Sukina Ismael Rawashdeh, Abdullah Mahmoud Saadeh, Hamzeh Ibrahim Al-Balas

Division of Cardiac Surgery and Cardiology, Princess Muna AL-Hussein Cardiac Center, King Abdullah University Hospital and Jordan University of Science and Technology, Irbid, Jordan

Am J Case Rep 2016; 17:412-416

DOI: 10.12659/AJCR.897998

Available online:

Published: 2016-06-17


BACKGROUND: Behçet’s disease (BD) is a chronic multi-systemic disease of unknown cause. Intra-cardiac thrombus (ICT) complicating BD is extremely rare. In general, cardiac manifestations in BD are associated with poor prognosis. Chest computed tomography (CT) scan and echocardiogram are excellent modalities for diagnosis and patient assessment. Cardiac surgical intervention can be done safely using an on-pump technique when medical management has failed.
CASE REPORT: We report on a case of a 27-year-old Jordanian woman diagnosed with BD who presented with dyspnea, cough, and hemoptysis, with supine bradycardia reaching 36 beats/minute and dizziness which disappear on sitting or standing position, and with heart rate reaching 76 beats/minute. Right atrial thrombus was identified using transthoracic echocardiogram and chest CT scan. After medical management failed, cardiac surgical intervention became an option and targeted extraction of the right atrial thrombus compressing the sinoatrial node (SA node).
CONCLUSIONS: In BD, right atrial thrombus compressing the SA node is rare. If conservative management has failed, cardiac surgical intervention removing the mechanical cause can be done safely, either using on-pump with cross clamp or on-pump with beating heart technique.

Keywords: Behcet Syndrome - complications, Adult, Heart Atria - surgery, Heart Diseases - surgery, Sinoatrial Node - physiopathology, Supine Position - physiology, Thrombosis - surgery



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