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Medical Science Monitor Basic Research


Extensively Drug-Resistant Tuberculosis: Report and Literature Review on Two Cases Requiring Prolonged Treatment

Unusual clinical course, Patient complains / malpractice, Educational Purpose (only if useful for a systematic review or synthesis)

Martha Matos-Tocasca, Gabriel De la Cruz-Ku, Erick Auccacusi, Diego Fernandez-Salas, Tatiana García-Ahuanari, Bryan Valcarcel-Valdivia

Peru Medical College of Peru, Lima, Peru

Am J Case Rep 2016; 17:819-826

DOI: 10.12659/AJCR.900001

Available online: 2016-11-03

Published: 2016-11-03


BACKGROUND: Extensively drug-resistant tuberculosis (XDR-TB) is a global problem due to the high morbidity and mortality it causes. Peru is one of the countries with the highest numbers of cases of XDR-TB, which increase every year.
CASE REPORT: We present the case of two siblings who developed XDR-TB, underwent surgery twice, and were in individualized treatment for more than 6 years. Finally they achieved remission of symptoms, despite not having standardized treatment schemes during their diagnosis period.
CONCLUSIONS: Extensively drug-resistant tuberculosis can be cured with a treatment that involves both medical care and patient actions to achieve remission of the disease.

Keywords: Extensively Drug-Resistant Tuberculosis, Mycobacterium tuberculosis, Tuberculosis, Multidrug-Resistant