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Medical Science Monitor Basic Research


Uncomplicated Cystitis in an Adult Male Following Influenza B Virus Infection

Unusual clinical course, Educational Purpose (only if useful for a systematic review or synthesis)

Robert J. Allen, Marios Koutsakos, Aeron C. Hurt, Katherine Kedzierska

Australia Department of Microbiology and Immunology, University of Melbourne, at Tthe Peter Doherty Institute of Infection and Immunity, Melbourne, VIC, Australia

Am J Case Rep 2017; 18:190-193

DOI: 10.12659/AJCR.902172

Available online:

Published: 2017-02-22

BACKGROUND: Influenza B viruses cause seasonal epidemics of respiratory illness, circulating concurrently with influenza A viruses. However, virological and clinical knowledge of influenza B viruses is less well advanced than for influenza A, and in particular, complications associated with influenza B infection are not as commonly reported. Complications of influenza B infection predominantly include neurological and musculoskeletal pathologies, while a review of the literature shows that bacterial infections associated with influenza B viruses often involve Gram-positive organisms, with a smaller subset featuring Gram-negative species.
CASE REPORT: In this case report we highlight an uncomplicated infection of the urinary tract by Escherichia coli immediately following influenza B infection, in an otherwise healthy adult white male with no prior history of urinary tract infection or structural abnormalities of the renal tract.
CONCLUSIONS: Bacterial infections complicating influenza B infection may include organisms not commonly associated with the respiratory system, such as Escherichia coli. In addition, bacterial complications of influenza B infection may affect non-respiratory systems, including the genitourinary tract.

Keywords: Gram-Negative Bacterial Infections, Influenza B virus, Urinary Tract Infections