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Medical Science Monitor Basic Research


Synchronous Gastrointestinal Carcinoid Tumor and Colon Adenocarcinoma: Case Reports and Literature Review

Challenging differential diagnosis, Clinical situation which can not be reproduced for ethical reasons, Rare co-existance of disease or pathology

Jessica N. Winn, Anjana Sathyamurthy, Jessica L. Kneib, Jamal A. Ibdah, Veysel Tahan

USA Division of Gastroenterology and Hepatology, University of Missouri, Columbia, MO, USA

Am J Case Rep 2017; 18:626-630

DOI: 10.12659/AJCR.903580

Available online:

Published: 2017-06-06


BACKGROUND: Coexistence of carcinoid tumor and colorectal adenocarcinoma is rare. In this report, we present two cases and review the current literature for synchronous carcinoid tumor and colorectal carcinoma occurrence.
CASE REPORT: In both cases, the rectal carcinoid tumors and sigmoid colon adenocarcinomas were detected by colonoscopy. The colon adenocarcinomas were effectively treated with a laparoscopic sigmoidectomy and the carcinoids were successfully removed endoscopically. Our 40-year-old patient was the youngest among 17 reported patient cases.
CONCLUSIONS: These two cases demonstrate that the diagnosis of gastrointestinal carcinoid requires a complete assessment of the remainder of the colon for another primary cancer to achieve a timely treatment management strategy.

Keywords: Adenocarcinoma, Carcinoid Tumor, Colonic Neoplasms, Neoplasms, Multiple Primary, neuroendocrine tumors