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Isolated Testicular Metastasis from Prostate Cancer

Unusual clinical course, Challenging differential diagnosis, Diagnostic / therapeutic accidents, Educational Purpose (only if useful for a systematic review or synthesis)

Alberto Bonetta, Daniele Generali, Silvia Paola Corona, Gianni Cancarini, Sarah Grazia Brenna, Chiara Pacifico, Giandomenico Roviello

Department of Radiotherapy, Cremona Social and Territorial Health Company (ASST), Cremona, Italy

Am J Case Rep 2017; 18:887-889

DOI: 10.12659/AJCR.904521

Available online:

Published: 2017-08-14

BACKGROUND: Prostatic adenocarcinoma is the most frequently diagnosed carcinoma in the male population; the most common sites of secondary lesions are nodes, bones, and lungs. We report the clinical case of a 58-year-old man presenting with a single metastasis in the left testis after a radical prostatectomy/lymphadenectomy for prostate cancer.
CASE REPORT: This clinical report focuses on a 58-year-old man with prostate cancer who developed an uncommon single metastasis in the left testis after radical surgery and adjuvant pelvic radiation therapy.
CONCLUSIONS: Prostate-specific antigen (PSA) levels are important in the follow-up of prostate cancer. At the same time, physical examination of all possible sites of metastasis and proper evaluation of all signs/symptoms are indispensable in the process of identifying recurrence and for the selection of patients undergoing adjuvant therapy.

Keywords: Neoplasm Metastasis, Prostatic Neoplasms, Testis