Scimago Lab
powered by Scopus
eISSN: 1941-5923
call: +1.631.629.4328
Mon-Fri 10 am - 2 pm EST


Medical Science Monitor Basic Research


Congenital Cystic Adenomatoid Malformation Diagnosed During First-Trimester Ultrasound Scan

Challenging differential diagnosis, Diagnostic / therapeutic accidents, Unusual setting of medical care, Congenital defects / diseases

Georges A. Markou, Georgios Dafereras, Christophe Poncelet

France Department of Obstetrics and Gynecology, Rene-Dubos Hospital, Cergy-Pontoise, France

Am J Case Rep 2018; 19:1-4

DOI: 10.12659/AJCR.906832

Available online:

Published: 2018-01-01


BACKGROUND: Congenital cystic adenomatoid malformation (CCAM) is mostly reported from the second trimester of pregnancy. We report a case of a microcystic type of CCAM that was suggested by routine ultrasound examination at a gestational age of 12 weeks.
CASE REPORT: First-trimester ultrasound screening revealed the presence of a hyperechoic image that occupied the whole of the right lung, without no other any associated complications. The cardiac and aorta deviations with diaphragmatic eversion associated with a poly-hydramnios had subsequently appeared. The diagnosis of CCAM was confirmed histologically after termination of the pregnancy at 25 weeks of gestation.
CONCLUSIONS: CCAM may occur at a very early stage of fetal lung development.

Keywords: Congenital Abnormalities, Cystic Adenomatoid Malformation of Lung, Congenital, Fetus, Prenatal Diagnosis