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Medical Science Monitor Basic Research


A Case of Umbilical Artery Thrombosis in the Third Trimester of Pregnancy

Unknown ethiology, Challenging differential diagnosis, Diagnostic / therapeutic accidents, Unusual setting of medical care

Fouad Lutfallah, Nina Oufkir, Georges A. Markou, Delphine Frimigacci, Christophe Poncelet

France Department of Obstetrics and Gynecology, René-Dubos Hospital Center, Pontoise, France

Am J Case Rep 2018; 19:72-75

DOI: 10.12659/AJCR.906859

Available online:

Published: 2018-01-19


BACKGROUND: Umbilical artery thrombosis is an extremely rare complication during pregnancy. Umbilical artery thrombosis has a poor prognosis and is associated with increased rates of perinatal morbidity, including intrauterine growth restriction (IUGR), and fetal mortality.
CASE REPORT: We report a rare case of umbilical artery thrombosis, diagnosed by ultrasound, at 33 weeks gestation in a 30-year-old woman who had previously had an uneventful pregnancy.
CONCLUSIONS: Umbilical artery thrombosis is a rare complication of pregnancy that is associated with high fetal mortality. Management may include planned elective delivery by cesarean section, following antenatal corticosteroid therapy for fetal lung maturation.

Keywords: Prenatal Diagnosis, Thrombosis, Umbilical Arteries