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Medical Science Monitor Basic Research


Diffuse Alveolar Hemorrhage without Extrapulmonary Manifestations: A Rare Presentation of Lupus

Unusual clinical course, Challenging differential diagnosis, Management of emergency care, Educational Purpose (only if useful for a systematic review or synthesis)

Bharat Bajantri, Binita Sapkota, Sindhaghatta Venkatram

USA Division of Pulmonary and Critical Care, Department of Medicine, Bronx Lebanon Hospital Center, Bronx, NY, USA

Am J Case Rep 2018; 19:218-223

DOI: 10.12659/AJCR.907148

Available online:

Published: 2018-02-28


BACKGROUND: Diffuse alveolar hemorrhage (DAH) is a life-threatening disorder resulting in hemorrhage into the lungs due to a variety of reasons. The underlying etiology for DAH is broadly divided into immune and non-immune mediated causes. Rheumatological disorders account for a small number of cases. Although hemoptysis is one of the alarming symptoms of DAH, it is absent in a third of the cases. Diagnosis often requires a conglomerate of history, clinical, and laboratory investigation and radiological studies.
CASE REPORT: We describe a case of a 31-year-old female who had an atypical presentation of systemic lupus erythematosus (SLE) with primary lung involvement/DAH and no other organ involvement.
CONCLUSIONS: This case report illustrates the importance of awareness and early recognition of the complication that can prevent mortality.

Keywords: Bronchoalveolar Lavage Fluid, Hemorrhage, Lupus Erythematosus, Systemic