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Periampullary Neuroendocrine Tumor as a Cause of Acute Pancreatitis

Challenging differential diagnosis, Rare disease

Gregory Nicolas, Haydar Nasser, Juliano Haddad, Elie Zaghrini, Karim Daher, Amal Assef Nasser, Christian Saliba, Nour Gharios, Raja Wakim

Department of Surgery, Lebanese American University Medical Center, Beirut, Lebanon

Am J Case Rep 2018; 19:1063-1067

DOI: 10.12659/AJCR.908205

Available online:

Published: 2018-09-05

BACKGROUND: Duodenal and ampullary carcinoids are very rare tumors accounting respectively for 2% and 0.03% of all carcinoid tumors. Clinical findings vary according to the location of the tumor within the periampullary region; with epigastric pain being the most common presenting symptom in duodenal carcinoids and jaundice the most common clinical finding in ampullary carcinoids. Treatment options include pancreaticoduodenectomy, local excision, and endoscopic excision.
CASE REPORT: In this case report, we present a 60-year-old male who presented with a one-week history of intractable epigastric pain. He was diagnosed with duodenal periampullary carcinoid tumor and treated with local excision.
CONCLUSIONS: Although duodenal and ampullary carcinoid tumors may have different clinical presentations, as well as histochemistry characteristics and metastatic potential, they appear to benefit from the same surgical treatment.

Keywords: Carcinoid Tumor, general surgery, Pancreatic Neoplasms