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Medical Science Monitor Basic Research


Silent Neoplastic Cardiac Invasion in Small Cell Lung Cancer: A Case Report and Review of the Literature

Rare coexistence of disease or pathology

Ngoc Pham, Mark D. Bonnen, Yohannes T. Ghebre

USA Department of Radiation Oncology, Baylor College of Medicine, Houston, TX, USA

Am J Case Rep 2018; 19:619-622

DOI: 10.12659/AJCR.908374

Available online: 2018-05-30

Published: 2018-05-30


BACKGROUND: Secondary malignant tumor of the heart is one of the most life-threatening complications of lung cancer. Several published case reports have documented non-small cell lung cancer (NSCLC) patients with neoplastic cardiac invasion. However, the number of reported cases of small cell lung cancer (SCLC) with neoplastic cardiac invasion is limited.
CASE REPORT: We present a rare case of advanced SCLC in a patient with asymptomatic neoplastic cardiac invasion. We also discuss radiation therapy modalities that should be considered in SCLC patients with cardiac invasion.
CONCLUSIONS: Clinicians should be vigilant about cases of SCLC with asymptomatic intra-cardiac invasion and practice caution when diagnosing, as well as treating with radiation as a monotherapy.

Keywords: Lung Neoplasms, Neoplasm Metastasis, Radiation, Small Cell Lung Carcinoma