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Silent Neoplastic Cardiac Invasion in Small Cell Lung Cancer: A Case Report and Review of the Literature

Rare co-existance of disease or pathology

Ngoc Pham, Mark D. Bonnen, Yohannes T. Ghebre

Department of Radiation Oncology, Baylor College of Medicine, Houston, TX, USA

Am J Case Rep 2018; 19:619-622

DOI: 10.12659/AJCR.908374

Available online:

Published: 2018-05-30

BACKGROUND: Secondary malignant tumor of the heart is one of the most life-threatening complications of lung cancer. Several published case reports have documented non-small cell lung cancer (NSCLC) patients with neoplastic cardiac invasion. However, the number of reported cases of small cell lung cancer (SCLC) with neoplastic cardiac invasion is limited.
CASE REPORT: We present a rare case of advanced SCLC in a patient with asymptomatic neoplastic cardiac invasion. We also discuss radiation therapy modalities that should be considered in SCLC patients with cardiac invasion.
CONCLUSIONS: Clinicians should be vigilant about cases of SCLC with asymptomatic intra-cardiac invasion and practice caution when diagnosing, as well as treating with radiation as a monotherapy.

Keywords: Lung Neoplasms, Neoplasm Metastasis, Radiation, Small Cell Lung Carcinoma